Explore the Extracellular Matrix using a Biocolor Kit

Biocolor's background was originally Extracellular Matrix research so naturally it's a subject we are passionate about!

Please use the headings below to learn more about this ever-evolving area of research.
What is the Extracellular Matrix (ECM) ?
The ECM has been likened to a ‘glue’ that binds cells together in connective tissues.
What does it do?
It provides necessary biomechanical support to tissues, is responsible for the physical and biochemical maintenance of all cells within an organism, and plays a key role in cellular processes such as cell proliferation, differentiation and migration.
What is the ECM composed of?
The Extracellular Matrix (ECM) is a fundamental part of living organisms, composed primarily of water, proteins, and polysaccharides. Its main structural proteins are fibrous in nature, with collagen and laminin being key examples. This fibrous network holds hydrogel-forming molecules such as the glycosaminoglycans, heparin and hyaluronic acid. A diverse range of other molecules are also present, including growth factors and Matrix Metalloproteases (MMPs).
Why analyse the ECM?
Analysing the Extracellular Matrix (ECM) helps us understand how organisms develop and age, as well as finding ways to treat diseases like cancer. Through advancements in Bioengineering, we hope to control ECM formation for fixing damaged tissues. Purified ECM components are becoming increasingly valuable in industries such as food production and cosmetics.